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Some people with bipolar disorder say that taking a GLP-1 has helped their mental health, while others say theyve noticed negative effects

Starting directly at 0.5 mg is sometimes possible depending on clinical circumstances, but this decision should always be made by a healthcare provider

In this guide, we explain what these peptides are, what the science says so far, the risks you should know about, and what changed with the FDA in 2026

Final thoughts When it comes to expired semaglutide, the safest approach is simple: when in doubt, throw it out