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High-dose Vitamin B12 May Improve ALS Prognosis if Started Early, Study Suggests Written by | Treatment with ultra-high-dose methylcobalamin, the physiologically active form of vitamin B12, may improve the prognosis of patients with amyotrophic lateral sclerosis (ALS) who receive it a year or less after symptom onset, a long-term study of Japanese reports
Laboratory research has examined its interaction with nitric oxide (NO) pathways, growth factor modulation including VEGF and EGF, and the FAK-paxillin signaling cascade used in tissue remodeling studies
Symptoms related to a lack of vitamin B12 include: Extreme tiredness Shortness of breath Nervous system issues, including numbing sensations or pins and needles Muscle weakness that may cause trouble walking and uncontrolled movements Mouth ulcers Sore tongue Neurological and psychiatric problems, including irritability, depression, confusion, changes in personality, depression, anxiety, and memory loss Vision problems Lack of energy Digestive issues, including nausea, vomiting, diarrhea, loss of appetite, or indigestion The Benefits of Getting Our B12 Shots in St
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