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Thus, since several mutations affecting the functional domains of p62 have been identified in patients with ALS and frontotemporal dementia, it has been demonstrated that p62 variants exhibit reduced KEAP1-binding, preventing NRF2 from entering the nucleus and promoting protective genes, and predisposing the cell death upon exposure to ROS [250, 251]
Association of semaglutide with retained gastric contents on endoscopy: retrospective analysis
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-EC and GSH standards and UDE enhanced SH-SY5Y intracellular GSH content In our previous investigation, we identified the protective effect of a 4 h incubation with 100 M of -EC, GSH, or UDE containing 100 M -EC against oxidative damage caused by H 2 O 2
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