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Sample size calculations were based on phase 2 trial data, which predicted a treatment difference of 1.0 in the Female Sexual Function Index-desire domain (FSFI-D) score and about 20.43 points in the Female Sexual Distress Scale-Desire/Arousal/Orgasm (FSDS-DAO) item 13, with a total of 450 evaluable patients providing sufficient statistical power to detect significant differences

While gastrointestinal issues are common, rarer serious side effects, such as pancreatitis or gallbladder problems, can occur

It prompts your pancreas to release insulin after you eat, which slows down your digestion and keeps you fuller for longer

The estimated absolute increase in the risk for NAION with GLP-1 therapy was 2.6 per 100,000 patient-years

For once-weekly GLP-1 medications, maintain minimum intervals between doses (48 hours for semaglutide, 72 hours for dulaglutide)