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In cultured hippocampal neurons, Dihexa treatment for 5 days induced a near 3-fold increase in the number of actin-enriched spines by 41 spines/50m for Dihexa vs
Raven LM, Stoita A, Feller RB, Brown C, Greenfield JR
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The authors suggest that the GLP-1-estradiol compound allows targeted delivery of estradiol to the CNS
Observations occurring after rescue therapy with other antihyperglycaemic treatment or prematurely stopping study drug were also excluded
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