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doi: 10.1016/S2213-8587(20)30344-2 25 HtooPTTesfayeHSchneeweissSWexlerDJEverettBMGlynnRJet al

Large doses of nicotinic acid have been observed to impair glucose tolerance, likely because of a decrease in insulin sensitivity

Power is reduced by focusing on obesity class subgroups as compared to the main analysis, but the findings were consistent across obesity categories with no evidence for heterogeneity of treatment effects

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[17] [18] Resistance training is especially important to minimize loss of muscle mass and maintain metabolic rate during weight loss