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The mechanism behind GLP-1 medications involves their interaction with the gastrointestinal tract, where they can alter motility and affect how quickly food moves through the digestive system
Sin embargo, debe considerarse en personas con factores de riesgo como uso de metformina, dieta vegetariana, ciruga gastrointestinal previa o edad avanzada
Meet our doctors Last reviewed: 19 Jun 2026 Sources Effectiveness of Dulaglutide in the Real World and in Special Populations of Type 2 Diabetic Patients (2020) NIH [accessed 27 January 2026] Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial (2023) The Lancet [accessed 27 January 2026] How to use Mounjaro (2023) Mounjaro [accessed 27 January 2026] Lillys SURMONT-2 results published in The Lancet show tirzepatide achieve a mean weight reduction of 15.7% at the highest dose (15mg) in adults with obesity or overweight and type 2 diabetes (2023) Lillys INVESTORS [accessed 27 January 2026] MHRA authorised diabetes drug Mounjaro (tirzepatide) for weight management and weight loss (2023) GOV.UK
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Final Thoughts: Why Injections Lead, But Pills Still Have a Place While injectable GLP-1 medications continue to deliver the most consistent and powerful results, especially for weight loss and cardiovascular benefits, its important to acknowledge that oral options like Rybelsus still play a meaningful role in patient care
