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doi: 10.1016/j.cca.2024.119857 284 ZhangJZhangYWangJXiaYZhangJChenL
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The most common switches are: POM to P : Occurs when the medicine no longer meets the legal criteria requiring prescription control (e.g., the risk of misuse or danger to human health without medical supervision is minimal)
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In addition to neural connections, the central clock system also synchronizes the circadian rhythms of the peripheral clock system through hormones or factors, such as arginine vasopressin (AVP) and tumor necrosis factor (TNF) ( FIGURE 1 The clock system mainly regulates metabolism in the following three ways
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