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Based on existing literature, an N of 6 was initially tested for DMRS in both groups and the fMRI group of GLP-1R KO mice, an N of 7 for PET in both groups [30,31,32,33], and an N of 6 for both groups for cyclic adenosine monophosphate (cAMP) measurement

FIGURE 1 Allicin, metformin, and their combination attenuate cardiac enzyme alterations in a rat model of doxorubicin-induced cardiotoxicity Serum cardiac injury biomarkers (CK-MB, LDH, and cTn-I) were markedly elevated in the DOX group compared with the control (p 0.05), whereas cTn-I remained mildly elevated (p = 0.0333 vs