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Top Research Studies on GLP-1s and Cardiovascular Outcomes The November 2023 issue of The New England Journal of Medicine shared results from a research study (SELECT) involving 17,000 patients that showed the use of semaglutide was linked to a 20% reduction in the risk of major adverse cardiovascular events such as heart disease, stroke and peripheral arterial disease in patients who had previously been diagnosed with heart disease

Selection of glucose-lowering medication with cardioprotective effect in older adults Sodium-glucose cotransporter (SGLT) 2 inhibitors and glucagon-like peptide 1 receptor agonists (GLP-1RA) are prominent glucose-lowering agents that have been confirmed to reduce cardiovascular events in patients with type 2 diabetes at high cardiovascular risk

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One of their effects is to slow down the rate at which food moves through the stomach to the small intestines