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A 2023 study published in the Journal of Clinical Endocrinology and Metabolism found that GLP-1 receptor agonist therapy in women with obesity and insulin resistance produced significant improvements in androgen levels, menstrual regularity, and metabolic markers, with effects most pronounced in women with baseline hyperinsulinemia, underscoring how tightly GLP-1 mechanisms are connected to broader hormonal function in women
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This increase reflects a pattern of growing use of newer GLP-1s, such as Ozempic and Mounjaro, while use of older products, such as Byetta (approved in 2005), Victoza (approved in 2010), and Trulicity (approved in 2014), has declined
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