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It is well-estabished that PPAR- agonists promote peroxisomal proliferation which can cause liver hypertrophy in rodents, but not humans 94
(Many more take them for other indications.) According to the Kaiser Family Foundation, public awareness has ramped up, with 32% of adults now saying they have heard a lot about these drugs
By promoting feelings of fullness, slowing gastric emptying, and reducing appetite, it supports weight loss for individuals who are overweight or obese
However, symptoms that persist beyond the initial adjustment period, worsen over time, or significantly impact your quality of life warrant professional evaluation
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