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For many of these uses, high-quality human evidence and long-term safety data are limited or unavailable

Although GLP-1 receptor agonists are mostly intended to be diabetes drugs, they are now being used not just for managing blood sugar but also for treating obesity and aiding in long-term weight management

The gut is often called the "second brain" because it contains so many neurons

It is typically prescribed when other glucose-lowering therapies, such as metformin, have not achieved adequate glycaemic control

Some people may notice blood pressure changes earlier, especially if they lose weight, reduce sodium intake, improve sleep, increase activity, or drink less alcohol