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Sandsdal, R
Subsequently, both were approved for weight loss in patients with overweight and obesity, this time under the names of Zepbound and Ozempic
the critical factors are when the target is achieved and whether a relatively stable weight and metabolic state can be maintained during the discontinuation washout period
Life Sci 74(18):22372249 Maquart FX et al (1990) Stimulation of collagen synthesis in fibroblast cultures by a triterpene extracted from Centella asiatica
Reported side effects included: Nausea (most common, particularly during dose escalation) Vomiting Diarrhea Constipation Decreased appetite (this is also the mechanism, so it is both a side effect and the goal) Discontinuation due to side effects in the Phase 2 trial was around 16% in the highest dose group
