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Finally, exendin-4-induced activation of both WT and V229A GLP-1R tended to reduce the diffusion of lipids at the plasma membrane labelled with the environmentally sensitive Laurdan probe (34) (Figure 4D), with no differences in Laurdan lateral diffusion between WT and V229A
It establishes a robust yet adaptable coordination with Cu(II) ions, utilizing the amino group of glycine, the imidazole nitrogen of histidine, and the -amino group of lysine
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