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Insurers raised cost-sharing sharply for GLP-1s in recent years, Klebanoff found

The evidence base behind it is much thinner than the marketing suggests

While useful as intermediate outcomes and for early-response monitoring, a key issue with biomarkers is the lack of a direct link to functional or quality-of-life outcomes

: The effect of l-carnitine supplementation on lipid profile and glycaemic control in adults with cardiovascular risk factors: A systematic review and meta-analysis of randomized controlled clinical trials Maryam Asadi et al

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