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In addition to its glycemic control benefits, tirzepatide has been associated with improvements in several cardiovascular risk factors
Stay hydrated and manage side effects Common side effects of GLP-1 agonists include nausea, constipation and feeling overly full
Table 2 summarizes RCTs of dual and triple GLP1-RA use in T2DM
According to the American Diabetes Association (ADA) Standards of Care, a GLP-1 RA should be considered in T2D patients who have not met glycemic goals on metformin, especially if additional factors are present such as atherosclerotic cardiovascular disease (ASCVD), heart failure, or chronic kidney disease
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