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Description

Ma JQ, et al

On April 30, 2026 , the FDA proposed leaving semaglutide, tirzepatide, and liraglutide off the 503B bulks list entirely, saying there is no clinical need for large-scale compounding

Altered dopaminergic transmission could contribute to feelings of anhedonia, reduced motivation, or in some cases, increased anxiety, particularly in individuals whose reward systems were heavily dependent on food-related dopamine release