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These are mechanistic observations within experimental systems, not claims about human physiology
IEM are a class of inborn errors of metabolic pathways that are marked by accumulation (and usually toxic) organic acid metabolites in blood (i.e., organic acidemias) and increased excretion of organic acids in urine (i.e., organic acidurias)
10.1161/ATVBAHA.117.309228 Arterioscler Thromb Vasc Biol
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