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The 0.25 mg maintenance dose was not studied as a long-term monotherapy in STEP trials, but it is the dose with the mildest side effect profile and still activates GLP-1 receptors meaningfully
Like most medications affecting the gastrointestinal system, tirzepatide can cause side effects, particularly when starting treatment or increasing dosage
Do not gulp large amounts at once, as this can trigger nausea on its own
A8: Due to its natural formulation, significant side effects are rare
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