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Quick Answer: Oral semaglutide typically requires 12-16 weeks to achieve maximal reductions in hemoglobin A1c, though some blood sugar improvements may appear within 2-4 weeks of starting treatment
Red flags include vomiting lasting more than a few hours, inability to keep any food or liquids down for 12+ hours, dizziness, or signs of dehydration like dark urine or extreme thirst
Randomized trials need to be designed to test that hypothesis directly, not inadvertently suppress it through exclusion criteria
In the meantime, please make sure you receive the quality medical care you deserve and that you're getting any medications from safe sources
Adequate levels support normal energy metabolism, which may help reduce fatigue related to deficiency
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