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DOI: 10.1016/j.freeradbiomed.2010.02.023 30
465,466 This activation is predominantly mediated through the disruption of the Kelch-like ECH-associated protein 1 (KEAP1) - NRF2 interaction (oxidation of KEAP1 Cys151, Cys273, and Cys288), 29 facilitating the translocation of NRF2 into the nucleus
Glutathione is the most efficient cellular tool for detoxification of medicines, pesticide substances and other xenobiotic substances and neutralize them before reaction with cellular elements like nucleic acids and proteins [27, 28]
El-Gendy, F
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