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doi: 10.3233/JPD-191729 94
Ipamorelins selective GHS-R1a agonism drives GH granule exocytosis from somatotrophs through Gq/11-PLC-IP3-calcium mobilisation , the identical intracellular signalling cascade engaged by non-selective first-generation GH secretagogues and but does so without producing the off-target receptor engagement at pituitary lactotrophs and corticotrophs that drives prolactin and cortisol co-secretion following GHRP-6 and GHRP-2 administration
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Once reconstituted, always refrigerate and use within the recommended timeframe
Lancet Psychiatry 4 , 295301 (2017)
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