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What may appear as tolerance is often attributable to other factors such as dietary adaptation, metabolic compensation, or progression of underlying disease rather than true receptor-level tolerance to the medication itself
That said, I think this is an interesting approval, but I do not expect it to dramatically reshape the GLP-1 landscape, he went on
The body processes injections and pills differently, which can impact how well the medication works
Discard the vial when its expiration or recommended in-use period is reached
doi: 10.1210/jc.2016-2962 99 BurmanPRitznEMLindgrenAC
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