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Zealand Pharma: ZP 8396 (Amylin analog) [65] In a randomized, double-blinded, placebo-controlled study, an amylin analog, ZP-8396, was investigated in a cohort of 56 male subjects, both lean and obese individuals
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Pathways enriched for DEGs selected from Gipr fl/fl vehicle versus Gipr Syn/ vehicle, as well as Gipr fl/fl vehicle versus Gipr fl/fl mGIPR-Ab/P1 comparisons, demonstrated that reduction of CNS GIPR function through either pharmacological or genetic intervention led to downregulation within adipose tissue of key canonical genes within these pathways (Fig
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