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Predicted expansion of the claudin multigene family
In research contexts, glutathione is studied for its role in neutralising reactive oxygen species, in the regeneration of other antioxidants, and in phase II detoxification through conjugation reactions catalysed by glutathione S-transferases
Further, kinetic studies of seleno-GPxs have revealed that the rate constant for the reaction of hydroperoxides with the selenolate of Sec is twothree orders of magnitude higher than the combined rate constant of the successive reactions of selenenic acid with the two molecules of GSH [8,9,10,11,12,13,14,15,16,17,18]
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