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This helps prevent sudden spikes or drops in blood sugar, which could interfere with your medications effectiveness
Michele Green in New York
however, if SGLT2is are not tolerated or are contraindicated, or if eGFR is less than adequate, a GLP-1RA with proven CV benefit can be added ( In recent guidelines on diabetes, prediabetes, and CVD from the European Society of Cardiology, in collaboration with the EASD, GLP-1RAs with proven CV benefit (liraglutide, semaglutide, and dulaglutide) are recommended as an add-on therapy to metformin ( Mechanisms for the Cardiovascular Benefits of GLP-1RAS Different mechanisms have been proposed to explain the CV benefits elicited by some GLP-1RAs ( 1c , body weight, and systolic blood pressure were also those associated with CV-event reduction
That ratio matters more than most people realize
Since the introduction of exenatide in 2005, more effective drugs have been developed that improve glycemic control, reduce weight, and decrease the occurrence of cardiovascular events
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