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Hypoglycemia overrides amylin-mediated regulation of gastric emptying in rats

4 How Mounjaro works Mounjaro activates two hormone receptors instead of one: Like Rybelsus, it activates the GLP-1 receptor It also activates GIP (glucose-dependent insulinotropic polypeptide), a second gut hormone involved in appetite regulation and blood sugar control This dual-action mechanism likely explains why tirzepatide produces greater weight loss and improvements in blood sugar in clinical trials than GLP-1-only medications

Most supplement products combine several ingredients , and a medication can interact with the product through any one of them

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