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The evidence below is per-compound, plus the CagriSema (cagrilintide + semaglutide) Phase 3 data as the closest analog
However, phase I and II clinical trial results have shown that although retatrutide has promising results for weight loss, it may have a few side effects to consider
The Gastrointestinal Safety of Orforglipron, a GLP-1 Receptor Agonist: A Network Meta-Analysis of Randomized Controlled Trials
Its capacity to significantly lower blood sugar levels makes it a widely chosen option for diabetes management
Still, formal clinical data specific to athletic performance is limited
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