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[10] ICH Q3C(R9) provides the main framework for classifying and controlling residual solvents

While the term specifically references Ozempic, it can happen with any form of accelerated weight loss, whether from medication, surgery, or extreme dieting

This medication targets the brains reward system and helps reduce cravings for food, which may make it easier to stick to a weight loss plan

Note that a GLP-1-FGF21 fusion protein exhibits enhanced glycemic and body weight control superior to combination therapy using separate analogs of GLP-1 and FGF21 (Boettcher, B.R