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The bioactive compounds in EOs help stabilize rumen pH and reduce the risk of subacute ruminal acidosis by controlling lactate-producing bacteria

Figure 9: Chronic liver disease (steatosis, steatohepatitis, and cirrhosis, respectively, based on severity of progression) is associated with decreased harvesting of energy and increased production of reactive oxygen species (ROS)

RSV administration has been associated with increased mRNA and protein expression levels of PGC-1 and SIRT1, promoting mitochondrial homeostasis, restoring respiratory capacity, and attenuating cellular injury (Zhang et al., 2020)

Therefore, we next explored whether modulating mitochondrial metabolism was sufficient to alter 5FU sensitivity