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GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the dual GIP/GLP-1 agonist tirzepatide provide the mechanism and the trial record, including STEP (NEJM 2021), SURMOUNT (NEJM 2022), and SURMOUNT-OSA (NEJM 2024)
Interestingly, inulin appeared to further potentiate both, the early-phase glucose-lowering and second-meal (35 h) appetite-suppressive effects of surgery when compared with MDX
Gallbladder issues: Be alert for pain in the upper right abdomen, jaundice, fever, or pale stools
GLP-1 drugs, however, seem more like a lanyard that holds your house keys, your car keys, your friends backup keys, your CVS rewards card, your work fob, and a mini Swiss army knife that has little tools on it that youve never actually figured out how to use