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This protective effect of L-carnitine is of utmost importance since increase in total cholesterol and triglyceride concentrations upon KD therapy has been previously reported in children 21

Optimizing delivery strategies remains another priority, given ASTs limited oral bioavailability

Based on clinical trial data from Novo Nordisk, people who took the pill along with maintaining a reduced-calorie diet and increased physical activity lost an average of 13% of their body weight over 64 weeks

Additionally, clinicians must consider comorbid conditions, concomitant medications, renal function, and patient preferences when integrating GLP-1RAs into treatment plans