labial melanotic macule dermoscopy macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight ⬆️ in single basal melanocytes; NO nests. More info like this in Dermoscopy of melanoma of the

Several critical enzymes that require ascorbate as a cofactor include the collagen processing enzymes, the lysyl hydroxylases and the prolyl hydroxylases as well as the catecholamine synthesis enzyme dopamine -hydroxylase

Shilpa: Liposomes 101 is a useful next step

Glutathione deficiency induces epigenetic alterations of vitamin D metabolism genes in the livers of high-fat diet-fed obese mice

In contrast, studies have shown that intrahippocampal injection of Tat in mice results in lower expression of claudin-5, indicating Tat-induced alterations in TJ protein expression in CNS microvessels [187]

If you are using oral glutathione, take it on a relatively empty stomach with water, ideally 30 minutes before food