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Additionally, injecting lentivirus expressing shRNA for lncRNA-H19 intra-articularly at the ankle of CIA mice ameliorates the progression of CIA by competitively binding with miR-124a, which directly targets CDK2 and MCP-1 (267)
If you decide to undertake self-injection, first consult a nurse practitioner or doctor to learn the proper method of identifying and cleaning the injection site, administration and how-to properly open and clean a vial.
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This method is sometimes used for deep tissue injuries or when targeting specific muscle groups
