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Despite promising results from existing randomized controlled trials of semaglutide and tirzepatide in those with obesity-related HFpEF, regulatory authorities and professional societies have not approved or endorsed the use of these drugs for HFpEF, due in part to the studies relatively small sample sizes and unknown generalizability
Glutathione is well-tolerated by most
R., & ATTAIN-1 Trial Investigators (2025)
Consult with your healthcare provider to determine a suitable maintenance plan based on your needs and health goals
GI side effects are worst during dose escalation (weeks 116) and improve significantly once maintenance dose is reached
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