glp 1 rhabdomyolysis The promise and peril of GLP-1 agonists: What we do (and don't) know as of August 2024 Weight Reduction with GLP-1 Agonists

A common example: a 5 mg vial reconstituted with 2.5 mL bacteriostatic water yields a concentration of 2 mg per mL, or 2,000 mcg per mL

Last Ozempic dose at five days, three days, and one day prior were independent risk factors for conversion to intubation (odds ratios, 2.09, 4.68, and 6.37, respectively)

Asanuma, M., Miyazaki, I

For tirzepatide (Zepbound) Jastreboff and colleagues reported in the New England Journal of Medicine in 2022 that at maximal doses, the percent of individuals reporting side effects were as follows: Nausea 31.0% Diarrhea 23.0% Vomiting 12.2% Constipation 11.7% Bettge and colleagues conducted a study published in Diabetes, Obesity, and Metabolism in 2017 that showed that individuals who were taking metformin while taking a GLP-1 were more likely to have side effects, especially nausea and vomiting

Insoluble fiber adds bulk and helps move waste through the intestines