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Laboratory and early clinical studies suggest that GLP-1 receptor agonists may dampen reward-driven behavior and reduce the salience of addictive stimuli

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Side effects from semaglutide (nausea, constipation) typically resolve within 48 weeks, whereas phentermine risks persist with long-term use

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Proper injection technique minimizes reactions: allow the medication to reach room temperature before injecting, insert the needle at a 90-degree angle, and avoid injecting into areas with existing irritation, scars, or stretch marks