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Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Collingridge et al., 2010
The peptides short half-life of 4-6 hours means twice-daily dosing produces more consistent tissue levels than single daily administration
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Supplementation reduced serum and tissue levels of ACE2, furin and TMPRSS2, which are considered host factors for SARS-CoV-2 entry into human cells