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Vixotrigine (BIIB074) : Vixotrigine is a state-dependent sodium channel blocker that targets hyperexcitable neurons involved in pain transmission

There was also a trend toward higher Gip expression in both sexes, which aligned with a recent report showing that insulin receptor signaling in IECs specifically regulates postprandial GIP but not GLP-1 (57)

Gastroenterology (2015) 149(2):37988