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Human clinical trials have not been completed, meaning efficacy and safety in people is not established through rigorous research
This is a critical advantage for individuals who want to manage body composition without the challenge of increased hunger that can occur with growth hormone-based approaches
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Some researchers eventually use up to 100mg daily for enhanced effects, though this should be approached gradually
First, it works through beta-3 adrenergic receptors, which are predominantly expressed in adipose tissue with limited expression in most other tissues
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