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Notably, inflammatory responses play a dual role in tumorigenesis: they can both promote malignant transformation and metastasis and exert an antitumour effect via pyroptosis induction [66]
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Ferritin and iron can promote the development of NAFLD through oxidative stress [24]
Poor sleep increases cortisol, drives insulin resistance, increases hunger hormones (even partially overriding GLP-1 appetite suppression), and impairs recovery from exercise
GLP-1 agonists work through similar mechanisms
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