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Serious side effects of weight loss peptides Serious side effects may also occur with GLP-1 medications, though they are rare and may include: Allergic reactions Inflammation of the pancreas (pancreatitis) Gallbladder problems Kidney problems Low blood sugar ( hypoglycemia ) in people with type 2 diabetes (especially when also using other medications that can lower blood sugar) Worsening of diabetic retinopathy (a condition that can cause blood vessel damage in the retina)in people with type 2 diabetes, particularly in those with pre-existing diabetic retinopathy Gastroparesis (severe slowing of stomach emptying) or, even more rarely, bowel obstruction GLP-1 medications contain a black box warning about the potential increased risk for certain thyroid tumors

The majority of the studies, 25 out of 29, were assessed as having a low-risk of bias

For women carrying extra weight, the appeal is not only the size of the loss but the way it targets appetite, blood sugar, and fat metabolism together

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