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The excessive cytosolic calcium activates apoptotic proteins such as calpain, calcineurin, and caspases, ultimately leading to cell death (Folkerts, Parks, Dedman, Kaetzel, Lyeth and Berman, 2007
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The information below is sourced from FDA published statements and the Federal Register and is provided for educational context, not as a prediction about altRx's specific operations
The nasal route also offers a direct portal to deliver substances directly into the brain via neuron pathways without being encumbered by the limitations of the blood-brain barrier
58 As an APC, especially myeloid DCs have been shown to induce T cell differentiation
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