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in vitro and animal studies have linked thymosin beta-4 overexpression to increased tumor size and metastasis in several cancer types (including colorectal and pancreatic cancer), leading researchers to flag a theoretical cancer-promotion risk, particularly for anyone with an active malignancy or recent cancer history Self-reported effects compiled from user and case reports, not controlled trials, include injection-site redness or itching, transient fatigue, and headache
Initially developed for managing type 2 diabetes, semaglutide was found to be effective for weight management and is only injected once weekly
Andreozzi, G
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However, retatrutide is still investigational, so its long-term cancer safety profile has not yet been fully established
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