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Advances in myocardial energy metabolism: metabolic remodelling in heart failure and beyond

We then use mouse and human proximal kidney tubular cells (TKPTS and Human Kidney-2 (HK-2) cells) for in vitro mechanistic validation, exploring the regulation of RF and inflammation in H 2 O 2 -treated renal tubular cells by AuNP nanozymes and the characteristic genes

These findings support its potential as a scalable, population-level cardiometabolic intervention and highlight the need for system-level strategies to enhance access and uptake

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