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Occurred in 8.8% of participants on 9 mg and 20.9% on 12 mg, compared to 0.7% on placebo Dose-dependent (higher dose, higher risk) Generally described as mild Rarely led to discontinuation Why this matters: Dysesthesia was not reported in the Phase 2 trial

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Administration of Candida Albicans to dextran sulfate solution treated mice causes intestinal dysbiosis, emergence and dissemination of Intestinal Pseudomonas Aeruginosa and Lethal Sepsis

Shailendra Singh, Director of Bariatric Endoscopy at West Virginia University