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Some people taking GLP-1 drugs report less cravings for food and alcohol
Common side effects include nausea, vomiting, and constipation during initial dose escalation, typically resolving within 2-4 weeks
Pfizers $10B bet implies the company believes these eventualities are manageable or that the benefits (market share, IP, platform) outweigh risks
ICH Q1A(R2): Stability Testing of New Drug Substances and Products
The higher dose (50 mg/kg) showed superior effects, reducing ALT and AST by 74.7% and 70%, respectively, while increasing albumin by 155.6% compared to the TAA group, bringing these parameters closer to normal values (Figures 1AC)
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