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Clinical trials have provided us with some promising results, with patients attaining an average weight loss ranging from 8-15% of their body weight over several months
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GLP-1s Direct Biological Impact in the Brain Beyond their systemic metabolic effects, GLP-1 medications exert direct biological actions in the brain through widespread expression of incretin (GLP-1) receptors in regions critical for cognition, including the hippocampus, prefrontal cortex, and hypothalamus [14]
The mechanisms of action all combine so that you take in fewer calories and make more out of them energetically while making less out of them as fat
The patients who tend to benefit most from GLP-1 medications (oral or injectable) share certain characteristics: theyve usually tried behavioral approachesimproved diet, increased exercise, better sleepwithout achieving meaningful or sustainable weight loss
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