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The SCFA-producing species, including Faecalibacterium prausnitzii , Bacteroides spp., and Clostridium spp., are well-known bacterial genera for synthesizing butyrate, which plays a vital role in maintaining intestinal barrier integrity and decreasing inflammation

The primary endpoint in most SURPASS studies was the reduction of glycated hemoglobin (HbA1c) , a laboratory marker reflecting average blood glucose levels over the previous two to three months

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